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![]() The test is available at CVS.com and in 5,600 CVS Pharmacy locations as the week of April 19, with additional locations to follow. The box contains two tests which should be administered twice over three days with at least 36 hours between tests. 360bbb-3(b)(1), unless the declaration is terminated or authorization is revoked sooner.: Reliable fully at-home test for surveillance and frequent use delivers results in 15 minutes. The tests have been authorized only for the detection of proteins from SARS-CoV-2, not for any other viruses or pathogens, and are only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of in vitro diagnostics for detection and/or diagnosis of COVID-19 under Section 564(b)(1) of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. ![]() They have been authorized by the FDA under an emergency use authorization. It will be in select locations in RI and MA the week of April 19, with increasing availability on CVS.com and in most CVS Pharmacy locations by the end of May.Ībbott BinaxNOW COVID-19 Antigen Self-Test $23.99The BinaxNOW COVID-19 Antigen Self Tests have not been FDA cleared or approved. CVS Pharmacy is the first retailer to carry the Ellume Home Test Kit. The test delivers results in 15 minutes through a free app downloaded to a smartphone, without the need for a second test. 360bbb-3(b)(1), unless the declaration is terminated or authorization is revoked sooner.: The first rapid, fully at-home test to receive Emergency Use Authorization by the FDA for at-home use without a prescription. This product has been authorized only for the detection of proteins from SARS-CoV-2, not for any other viruses or pathogens, and is only authorized for the duration of the declaration that circumstances exist justifying the authorization of emergency use of in vitro diagnostics for detection and/or diagnosis of COVID-19 under Section 564(b)(1) of the Federal Food, Drug and Cosmetic Act, 21 U.S.C. ![]() The three testing options now available at CVS include:Įllume COVID-19 Home Test Kit $38.99The Ellume COVID-19 Home Test has not been FDA cleared or approved but has been authorized by the FDA under an emergency use authorization. "CVS Health has been a leader in providing accessible testing in communities nationwide, and we continue to bring new solutions to market to ensure that consumers have a variety of COVID-19 testing options available to them." Making OTC COVID-19 tests available to our customers helps remove barriers by providing convenient options for testing," said George Coleman, Senior Vice President and Chief Merchant, CVS Pharmacy. "Access to testing continues to be an important part of the nation's pandemic response. These options provide customers with access to convenient testing that can be conducted at home and complement CVS Health's commitment to providing consumers with access to comprehensive COVID-19 testing services. All three tests have received FDA Emergency Use Authorization (EUA), do not require a prescription, and are intended for use by individuals with or without symptoms. The tests include the Ellume COVID-19 Home Test, the Abbott BinaxNOW COVID-19 Antigen Self Test and the Pixel by Labcorp PCR Test Home Collection Kit. CVS Pharmacy, the retail division of CVS Health (NYSE: CVS), today announced the availability of three over-the-counter COVID-19 testing options in stores and online. The index tracks a variety of census variables including poverty, lack of access to transportation, and crowded housing that may weaken a community’s ability to prepare for and recover from hazardous events like natural disasters and disease outbreaks,” CVS said.Retailer expands access to convenient, at-home testing options with new-to-market, home tests available in stores and online “More than half of the company’s 1,000 test sites will serve communities with the greatest need for support, as measured by the CDC’s Social Vulnerability Index. Testing will not take place inside any retail locations, but CVS Pharmacy, HealthHUB and MinuteClinic will continue to serve customers and patients even if the location is also serving as a testing site. ![]() Each substory can play out in multiple different ways based on your decisions, often causing serious consequences for your playthrough.
![]() Those were followed by banana splits in 1951, still one of their most popular menu items. The first foray beyond cones, sundaes, and tubs of ice cream were malts and shakes in 1949. But some of them are particularly memorable, especially their best-known treats. With nearly 80 years of history, there are a lot of milestones in the Dairy Queen story. The signature “curl” on every DQ cone, which is created with a twist of the wrist when serving it, has been passed down ever since. The secret to making it work was a modified custard machine that would keep this new creation at the right temperature and let them serve it up at will. The only ice cream you would find is what we now consider “hard” ice cream.īefore that fateful day when they sold 1,600 servings in two hours, the McCulloughs discovered that lowering the butterfat content of the ice cream, keeping it at a slightly warmer temperature, and mixing it with some air when serving it would let them serve the soft treat we all know and love. Up until the late 1930s, there was no such thing as “soft-serve” ice cream. There are nearly 6,000 locations across the globe now. They grew to 100 locations in 1947, and all the way to 2,600 by 1955.Ĭanada contributed to the massive growth over the eight-year span from 1947 to 1955, with the first Dairy Queen north of the border opening in 1953 in Estevan, Saskatchewan.ĭairy Queen continued to expand to countries around the world over the next several decades. The first Dairy Queen location opened in Joliet, Illinois in 1940. Over the course of two hours, they dished up more than 1,600 frozen treats, and people were hooked. John Fremont McCullough and his son Alex were testing a soft frozen dairy treat and convince a family friend, Sherb Noble, to let them sell the treat in his ice cream store. You can trace Dairy Queen’s history back more than 80 years to August 4, 1938. Information About Dairy Queen Canada’s Menu Where Did Dairy Queen Originate? Chicken Garden Greens Salad (Crispy or Grilled) As most of you know, I like to make that hero and heroine work for it for a while. That was perfect since I’m not that great at writing stand-alone romance stories anyway. Until I realized the obvious solution was to write three books. Maybe it would be a perfect project for a summer full of distractions.īut there was still the problem of a stand-alone novel being tough to market… It seemed like it could be a fairly short and simple story with just one point-of-view character. My mind came back to that inheriting-a-house-with-a-werewolf story. I had family coming to visit for the summer and a road trip planned, and I knew I’d have a hard time focusing on something long and involved. These were turning into some thick books by my standards (by most authors’ standards), and with numerous point-of-view characters, they were more complicated than the average story. I’d just finished the second, which had come in at something like 185,000 words, and Book 3 was looking meaty too. Oh, and don’t forget the space opera!īut then in May, I was in beast-mode, writing the third Dragon Gate novel and starting to feel like I needed a break. A random paranormal romance (as I was thinking of it then) among all the high fantasy, steampunk, and a single urban fantasy series. It also wasn’t going to be in a sub-genre of fantasy that I’d written in before, so I figured that might make it an even harder sell to my existing fans. ![]() With a stand-alone book… there’s none of that, unless you get lucky, and readers go check out your other stuff. With series, you can spend more than you earn from sales on advertising for Book 1 on the assumption that some readers will carry on and buy the next books. ![]() Also, it’s a big pain to actually get a stand-alone book to sell. I was deep in Death Before Dragons at the time with an idea for an epic fantasy - Dragon Gate - prodding me and wanting attention. I went as far as to order a cover for the book, but I didn’t put aside my other projects. What’s now Chapter 1 in Mind Over Magic is pretty close to how I imagined it a year ago. Because who just inherits a house without catches, right?Īnd because romances are always fun, I figured they’d hook up in the end (regular readers will know this is not new for me), but I couldn’t let that happen right away… I envisioned him leaping out at her car and trying to drive her off the property first. And the werewolf now known as Amar came along with the original idea. I actually had the idea for a woman inheriting a big rambling old house in a small town more than a year ago. What was the genesis of the story (yeah, I know, it’s super geeky to use words like genesis in every day conversation, but… you’ve read my books and know I love my words)? I thought it would be fun to do a little “behind the scenes” post to go along with the launch. Here are the links if you want to pick it up:Īnd if you haven’t read Book 1 (Mind Over Magic) yet, there’s a preview chapter on my blog here. Spell Hound, the second novel in my new A Witch in Wolf Wood series (or Wolf Woof as the faithful sidekick Lucky calls it), is out on Amazon this weekend. Various stories exist about piranhas, such as how they can dilacerate a human body or cattle in seconds. Shoals of piranhas can be found in numbers of up to 1000. These voraciously hungry fish tend to have a l urk-and-ambush style of attack that occurs en masse, with large groups of piranha feeding at once. They will also eat whatever meat crosses their path, and because they hunt in groups, they can take down large animals. Most piranhas are shy and non-aggressive, unless they are hunting or protecting their young.īlack piranhas and red-bellied piranhas are considered the most dangerous and aggressive toward humans.ĭespite the carnivorous nature of the piranha, the piranha is actually an omnivore and will eat almost anything that it can find.Ī typical piranha diet consists of insects, fish, crustaceans, worms, carrion, seeds, fruit and other plant material. But, while sharks replace their teeth individually, piranhas replace teeth in quarters multiple times throughout their lifespan. It’s not uncommon for piranhas to lose teeth throughout their lifetime. They have a distinct under-bite, which means the bottom row of teeth is constantly exposed. Piranhas range in color from yellow to steel-grey to bluish to partly red to almost black.Ī piranha’s mouth is lined with a single row of razor-sharp, triangular teeth. Piranhas are normally about 15 to 25 centimeters (6 to 10 inches) long, although some specimens have been reported to be up to 50 centimeters (20 inches) in length. rhombeus is a species complex, but molecular work to confirm this has yet to be undertaken.They live up to 25 years in the wild and 10-20 years in captivity. ![]() The morphological differences between populations suggest that S. When Bernard Germain de Lacépède created the genus Serrasalmus in 1803 the only species he placed in it was Salmo rhombeus, so this species is the type species of its genus. The redeye piranha was first formally described in 1766 as Salmo rhombeus with the type locality given as Brokopondo on the Suriname River in Surinam. At least when breeding they defend an area around the nest which is placed among thick vegetation. This is not a sociable species and normally lives solitarily. They are well known scavengers, and feed on carcasses within the river. They will also eat the scales and fins which they can nip off other fishes. These fish are opportunistic and omnivorous feeders which will eat plants, fallen fruits and animals smaller than themselves such as insects and small fishes. Paler coloured fish tend to be found in turbid white waters, while in clear or dark waters, dark fish predominate. The juveniles are most frequently recorded in stiller stretches where there is thick submerged or marginal vegetation. The redeye piranha occurs in a wide variety of habitats but the adults have a preference for the larger, deeper river channels where they normally hunt for prey either in deep stretches or in the vicinity of rapids. It has been introduced to Florida but is now extirpated. They are found in the drainage systems of the Amazon and Orinoco as well as the Essequibo River and other rivers of the Guiana Shield and the coastal rivers of northeastern Brazil. The redeye piranha is found in northern South America, east of the Andes. The maximum recorded fish measurement standard length is 41.5–61 centimetres (16.3–24.0 in), although a more normal length is around 32 centimetres (13 in), and they attain a maximum weight of 3.0 kilograms (6.6 lb). How dark the fish become depends on the local water conditions fish in Peru appear to be the darkest and may be almost jet black. As they mature their silvery body becomes less mottled and changes to a darker grey or black colour. ![]() The colour of juveniles can be more mottled than in adults. Whatever the body colour, this species has red eyes. It has a distinctively, rhombus-shaped body, solidly coloured from grey through to nearly black. The redeye piranha is the largest species of piranha. ![]() It is the type species of the genus Serrasalmus. The redeye piranha ( Serrasalmus rhombeus), also known as the black piranha, white piranha, spotted piranha or yellow piranha, is a species of freshwater ray-finned fish, a piranha from the family Serrasalmidae.
![]() Compounding the situation, HRLP never called me. To make matters worse she refused to give a copy of the report and said that their HRLP department would call me. She did not know how to use the PC and required help from an older employee. The lackadaisical store manager ignored the accident and after 30mins decided to write an accident report. Their monologue is "It's on sale, do you want to buy it?" This is all I heard when I looked around the store and an unfortunate accident occurred, breaking glass coffee table injuring my legs. Great merchandise but the worst customer service that I have ever experienced. The cons: Some complaints about longevity in some cases. The pros: Stylish dining tables and chairs with customization options. Customers have good things to say about Z Gallerie's dining tables overall, but there were some complaints around durability in some cases. Their seating offers upholstered options in both synthetic and leather options with European themes. Similar to other categories, Z Gallerie focuses on modern designs with both all-wood and metal frame options for prices that are moderate to high end. The last category that shoppers are excited to get their hands on is a new dining table or set. The cons: Some disappointment about perceived price value in some cases. The pros: Modern and luxurious style mirrors to make a statement. However, there were some disagreement about perceived value in some cases. With the main focus being silver and gold accents, most customers have good things to say about the designs. Their prices range in the middle to higher end at over $200 to start. Their mirror options come in both floor and hanging wall mirror designs with a focus on modern and luxury styles. The cons: Some complaints about longevity and durability in some cases.Īnother top request from shoppers is a new Z Gallerie mirror. The pros: Modern designed beds and storage units with luxury veneers. While most customers like the bed and bedroom set offerings by Z Gallerie, there were some complaints about durability and longevity in some cases. Some of their most popular designs feature tufted chesterfield style headboards, while their dressers and bureaus feature luxe-style veneers. Z Gallerie offers sleek and modern headboards, bed frames, and bedroom sets to choose from. The cons: Some complaints about price value.Īnother top item requested from Z Gallerie shoppers is a new bed or bedroom set. The pros: Wide range of unique, modern wall art to choose from. ![]() While most shoppers have good things to say about the styles, there were some disagreements about price value in some cases. Their selection is forward-thinking and offers shoppers modern or contemporary flair to their designs. Z Gallerie's wall art selection includes abstract art, fashion art, modern glitter art, and photographs. The second category that shoppers are eager to get a hold of is wall art. ![]() These virtual programs are typically 45 to 50 minutes and provide students and educators with opportunities to “visit” museums, national parks, zoos, aquariums and science centers. The Center for Interactive Learning and Collaboration (CILC) offers free community learning programs for students of all ages every weekday at 1 p.m. Some virtual field trip providers also charge a small fee. Educators must also have a decent microphone and be aware that field trip content providers may be in a different time zone. To participate in virtual field trips, educators and their students need internet access, a webcam (so the presenter can see the class), and a way to project an image on the whiteboard. It is important to note that virtual field trips are not without barriers. “I want to spark students’ curiosity so that they are inspired to go out and learn.” “Technology allows students to travel the world, both in time and space,” said Poor, who teaches elementary and middle school e-lessons. ![]() In addition, virtual field trips create enriching, interactive experiences that cater to students of all learning styles and expose them to diverse perspectives. They eliminate the need for transportation, decrease lost instruction time spent on travel, and involve fewer safety concerns (no permission slips required). Virtual field trips are not limited by distance and are typically more cost-effective than traditional in-person field trips. ![]() Jasmin Poor, virtual field trip coordinator at Roper Mountain Science Center in Greenville, South Carolina, recently described the value of virtual field trips to ISTE conference attendees. The virtual field trip has become a popular pedagogical strategy for connecting young people to enriching educational experiences from the comfort and safety of the classroom - or home. The move to remote learning during the COVID-19 pandemic has forced educators to find new and innovative ways to deliver curriculum to their students. ![]() Ophthalmology clinics of North America. (2003) Optineurin in primary open angle glaucoma. Sarfarazi, M., Rezaie, T.SNPs and Interaction Analyses of Noelin 2, Myocilin, and Optineurin Genes in Japanese Patients with Open-Angle Glaucoma. Funayama, T., Mashima, Y., Ohtake, Y., Ishikawa, K., Fuse, N., Yasuda, N., Fukuchi, T., Murakami, A., Hotta, Y., Shimada, N.The role of TIGR and OPTN in Finnish glaucoma families: a clinical and molecular genetic study. Forsman, E., Lemmelä, S., Varilo, T., Kristo, P., Forsius, H., Sankila, E.M., Järvelä, I.We show that optineurin has a K63- linked polyUb-binding region similar to that of NEMO, and like NEMO, it bound K63- but not K48-linked polyUb.Statistical analysis showed a possible interaction between polymorphisms in the OPTN and the TNF-alpha genes that would increase the risk for glaucoma. CONCLUSIONS: These findings demonstrated that the OPTN gene is associated with POAG rather than NTG in the Japanese.CONCLUSION: Data from this study do not support a strong role for the OPTN Met98Lys variant in glaucoma, ADOA or LHON.This rat clone was sequenced and the primary structure of the human homolog (termed TFIIIA-intP for TFIIIA -interacting protein) was determined from expressed sequence tags.The combination of OLFM2 /317G and OPTN /603A was significantly associated with elevated IOP (P = 0.018).Common polymorphisms in MYOC, OPTN, and APOE might interactively contribute to POAG, indicating a polygenic etiology.Cancer incidence associated with AZA versus CYA, CYA versus TAC, and AZA versus mycophenolate mofetil (MMF) is compared in both transplant center and registry reports including new, unreported Organ Procurement and Transplantation Network/United Network for Organ Sharing ( OPTN /UNOS) data from 1998 to 2003.Utilizing the UNOS/ OPTN (United Network for Organ Sharing/ Organ Procurement Transplantation Network) database, we analysed 112 971 kidney waiting list registrations added during 6/3/95-31/12/00, and 8162 HLA zero-mismatched (0 mm) primary kidney transplants in the USA during 1/1/ 88-31/3 /02.On nocodazole treatment, the OPTN foci were dispersed into the cytoplasm.OPTN expression is also induced 2.3-fold by TNFalpha and 2.6-fold by prolonged DEX treatment.If the reported mutation rates of OPTN in the LPG group can be confirmed in other LPG or POAG patients, then this gene would be useful in diagnosing presymptomatic persons many decades before they develop this silent and blinding eye condition. ![]() Īssociations of OPTN with chemical compounds In this study, we prospectively applied the MELD score to estimate 3-month mortality to 3437 adult liver transplant candidates with chronic liver disease who were added to the OPTN waiting list at 2A or 2B status between November, 1999, and December, 2001.AIMS: To investigate the role of the common OPTN Met98Lys variant as a risk allele in open-angle glaucoma (OAG), autosomal dominant optic atrophy (ADOA) and Leber's hereditary optic neuropathy ( LHON ).Therefore, identification of glaucoma-causing genes such as Myocilin, Optineurin, and others could provide molecular diagnostic tools for this category of optic neuropathy.SNPs and Interaction Analyses of Noelin 2, Myocilin, and Optineurin Genes in Japanese Patients with Open-Angle Glaucoma.Instead, two polymorphisms in the TIGR gene and three polymorphisms in the OPTN gene, in which one was novel, were found in three phenotypes : POAG, exfoliative glaucoma, and exfoliation syndrome. |
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